The fares are higher in Tahoe ($1.44/mi vs $0.87/mi), but the lack of pickups on the CA side and slow speed IMO make it worse than Reno. Speed limit is like 35 MPH and there are like 2-3 stoplights per mile. Especially with the non-existence of Surge. Back before they got rid of surge, (for the most part), I'd sometimes do better in Tahoe because it used to surge more in Tahoe than in Reno
Based on how much I made on Friday night in Tahoe, extrapolating that out to the 16 hour maximum on Uber... there was no way I could have possibly made $500 even if I worked all 16 hours. Last Friday I was in Tahoe but I've been in Reno for the 5 or so fridays before that and I can definitely tell you I would have made more in Reno.
But things change and sometimes you just get lucky or unlucky with ant-rider ratio.